Our research is supported by:
National Institutes of Health (grants R01 DC011277 (PI Chang), R21 DC015312 (PI Chang), and R21 DC015853 (PI Chow)), ASHFoundation Clinical Research Award, and the Matthew Smith Stuttering Research Fund.
Longitudinal study of brain development in children who stutter
This study involves collecting longitudinal data (behavioral, neuroimaging) from young children who stutter and their age-matched peers, starting from close to stuttering onset (ages 3 and up). Multiple acquisition of these data points from each child will enable us to examine brain developmental trajectories that differ between children who do and do not stutter, and further help elucidate factors that are associated with persistent forms of stuttering. We are also investigating how these brain and behavioral changes that correlate with persistent developmental stuttering differ between the two sexes.
These analyses will help us answer some long-standing questions about stuttering, such as: Why do some children recover naturally from stuttering while others don't? Why do more boys stutter than girls?
The findings from this research have potential to lead to objective prognostic markers for persistent stuttering, and also lead to targeted treatment related research that may involve neuromodulation.
This research is funded through an NIDCD/NIH grant R01 DC011277 (PI Chang).
Rhythm perception and production in people who stutter
Combining behaviorial experiments, neuroimaging, and animal modeling (songbirds) methods, we are conducting parallel series of studies to investigate a novel rhythm deficit hypothesis in stuttering. This study is in collaboration with Drs. Devin McAuley, Juli Wade, and Laura Dilley at Michigan State University.
This study is funded by the Grammy Foundation and the RAIND (Research in Autism, Intellectual, and Neurodevelopmental Disabilities) pilot grant (PIs McAuley, Chang, Wade, Dilley).
Read a related article on this research:
Other projects with U of M and outside collaborators
fNIRS-ERN study on the psychological and neurophysiological risk markers of persistent stuttering in early development (funded by the U of M Center for Human Growth and Development Rauner Family Pilot grant; PIs Fitzgerald and Chang): with Drs. Kate Fitzgerald, Yanni Liu
Brain connectivity analyses of multimodal imaging data from children who stutter: With Dr. Chandra Sripada and Mike Angstadt
Speech prosody perception in stuttering children and adults: With Dr. Laura Dilley
Imaging genetics study of twins who stutter: Collaboration with the MSU Twin Registry (Co-Is Kelly Klump and Alex Burt; funded by NIDCD R21DC015312 PI Chang)
Speech motor adaptation to auditory perturbation in children who stutter: With Drs. Frank Guenther, Ayoub Daliri, Shanqing Cai
Imaging-Genetics investigation of developmental stuttering: with Drs. Deryk Beal, Chris Bartlett, Jason Bohland (Currently funded by the Matthew Smith Stuttering Research fund)
tDCS (transcranial direct current stimulation) effects on speech motor learning: with Drs. Rachael Seidler, Marom Bikson, Alex DaSilva (Funded by ASHFoundation and the Matthew Smith Stuttering Research Fund)
Surface-based analysis of brain morphometry in children who stutter: With Drs. Jason Tourville and Frank Guenther